Startup Careers

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Sr. Bioinformatics Scientist at Synthego
Redwood City, CA, US
Synthego is seeking a Senior Bioinformatics Scientist to help us bring genome engineering solutions to an ever wider audience. You will collaborate with research scientists and software developers to create custom genome annotations and architect informatics pipelines that will accelerate the pace of gene editing research.
As a member of the bioinformatics team, you’ll work alongside an interdisciplinary group of researchers and engineers to design experiments, organize data, build models, and generate and test hypotheses to improve our understanding of CRISPR-based editing approaches and outcomes.

What You'll Do

    • Develop and maintain core bioinformatics resources relating to genome annotation and feature extraction with a strong emphasis on computational pipelines
    • Provide bioinformatics support for sgRNA guide design tools (sequence properties, off target editing)
    • Optimize design of sequences for knockout or knockin for research or clinical purposes
    • Work closely with the our research teams to discover more sophisticated descriptions of genomic variability
    • Create polished visualizations to communicate your results to a wider audience
    • Write high quality, robust source code with clear documentation

About You

    • PhD in Bioinformatics, Statistical Genetics, Genomics, or Computational Biology, or equivalent experience
    • 5+ years developing solutions for structural analysis, functional analysis, and custom annotation of whole genomes
    • Expert knowledge of genomic databases and analysis tools
    • Familiarity with CRISPR guide scoring and off-target prediction tools
    • Fluent in Python; comfortable in R
    • Ability to summarize, visualize, and communicate findings to non-scientists
    • Strong desire to work in a fast-paced, collaborative start-up environment

Nice to Haves

    • Experience with flow cytometry or CyTOF data
    • Experience developing APIs
    • Familiarity with relational and property graph databases

Company Benefits & Perks

    • Competitive salary
    • Generous equity at an early stage company
    • Robust medical, dental and vision benefits
    • 401k Plan
    • Fully stocked kitchen and snacks
    • Free catered lunches and dinners 
    • 4x daily Shuttle bus to & from San Francisco
Synthego’s vision is to turn biology into an information science, with the ultimate goal of dramatically extending the healthy human lifespan.
Synthego builds advanced bioinformatics and automated hardware platforms to create next-generation molecular biology tools, starting with full-stack genome engineering.
These world-class tools accelerate basic scientific discovery, critical disease cures and novel synthetic biology applications to improve and prolong life.